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1dc0

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[[Image:1dc0.gif|left|200px]]<br /><applet load="1dc0" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1dc0.gif|left|200px]]
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caption="1dc0, resolution 1.3&Aring;" />
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'''CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG'''<br />
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{{Structure
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|PDB= 1dc0 |SIZE=350|CAPTION= <scene name='initialview01'>1dc0</scene>, resolution 1.3&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1DC0 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DC0 OCA].
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1DC0 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DC0 OCA].
==Reference==
==Reference==
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The structure of a stable intermediate in the A &lt;--&gt; B DNA helix transition., Ng HL, Kopka ML, Dickerson RE, Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2035-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10688897 10688897]
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The structure of a stable intermediate in the A &lt;--&gt; B DNA helix transition., Ng HL, Kopka ML, Dickerson RE, Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2035-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10688897 10688897]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Dickerson, R E.]]
[[Category: Dickerson, R E.]]
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[[Category: intermediate]]
[[Category: intermediate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:15:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:36:02 2008''

Revision as of 08:36, 20 March 2008

Image:1dc0.gif


PDB ID 1dc0

Drag the structure with the mouse to rotate
, resolution 1.3Å
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF AN A/B-DNA INTERMEDIATE CATGGGCCCATG


Overview

The DNA dodecamer CATGGGCCCATG in a crystal structure of resolution 1.3 A has a conformation intermediate between A and B DNA. This trapping of a stable intermediate suggests that the A and B DNA families are not discrete, as previously believed. The structure supports a base-centered rather than a backbone-centered mechanism for the A <--> B transition mediated by guanine tracts. Interconversion between A and B DNA provides another means for regulating protein-DNA recognition.

About this Structure

1DC0 is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.

Reference

The structure of a stable intermediate in the A <--> B DNA helix transition., Ng HL, Kopka ML, Dickerson RE, Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2035-9. PMID:10688897

Page seeded by OCA on Thu Mar 20 10:36:02 2008

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