1dd5

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[[Image:1dd5.gif|left|200px]]<br /><applet load="1dd5" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1dd5.gif|left|200px]]
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caption="1dd5, resolution 2.55&Aring;" />
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'''CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA RIBOSOME RECYCLING FACTOR, RRF'''<br />
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{{Structure
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|PDB= 1dd5 |SIZE=350|CAPTION= <scene name='initialview01'>1dd5</scene>, resolution 2.55&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA RIBOSOME RECYCLING FACTOR, RRF'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1DD5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with <scene name='pdbligand=ACY:'>ACY</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DD5 OCA].
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1DD5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DD5 OCA].
==Reference==
==Reference==
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Crystal structure of Thermotoga maritima ribosome recycling factor: a tRNA mimic., Selmer M, Al-Karadaghi S, Hirokawa G, Kaji A, Liljas A, Science. 1999 Dec 17;286(5448):2349-52. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10600747 10600747]
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Crystal structure of Thermotoga maritima ribosome recycling factor: a tRNA mimic., Selmer M, Al-Karadaghi S, Hirokawa G, Kaji A, Liljas A, Science. 1999 Dec 17;286(5448):2349-52. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10600747 10600747]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: three-helix bundle]]
[[Category: three-helix bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:15:29 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:36:35 2008''

Revision as of 08:36, 20 March 2008


PDB ID 1dd5

Drag the structure with the mouse to rotate
, resolution 2.55Å
Ligands:
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA RIBOSOME RECYCLING FACTOR, RRF


Overview

Ribosome recycling factor (RRF), together with elongation factor G (EF-G), catalyzes recycling of ribosomes after one round of protein synthesis. The crystal structure of RRF was determined at 2.55 angstrom resolution. The protein has an unusual fold where domain I is a long three-helix bundle and domain II is a three-layer beta/alpha/beta sandwich. The molecule superimposes almost perfectly with a transfer RNA (tRNA) except that the amino acid-binding 3' end is missing. The mimicry suggests that RRF interacts with the posttermination ribosomal complex in a similar manner to a tRNA, leading to disassembly of the complex. The structural arrangement of this mimicry is entirely different from that of other cases of less pronounced mimicry of tRNA so far described.

About this Structure

1DD5 is a Single protein structure of sequence from Thermotoga maritima. Full crystallographic information is available from OCA.

Reference

Crystal structure of Thermotoga maritima ribosome recycling factor: a tRNA mimic., Selmer M, Al-Karadaghi S, Hirokawa G, Kaji A, Liljas A, Science. 1999 Dec 17;286(5448):2349-52. PMID:10600747

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