3okj
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
- | [[3okj]] is a 28 chain structure | + | [[3okj]] is a 28 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OKJ OCA]. |
==See Also== | ==See Also== |
Revision as of 12:11, 20 October 2012
Contents |
Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition
About this Structure
3okj is a 28 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
See Also
Reference
- Grawert MA, Gallastegui N, Stein M, Schmidt B, Kloetzel PM, Huber R, Groll M. Elucidation of the alpha-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition. Angew Chem Int Ed Engl. 2011 Jan 10;50(2):542-4. PMID:21154547 doi:10.1002/anie.201005488
Categories: Proteasome endopeptidase complex | Saccharomyces cerevisiae | Gallastegui, P. | Groll, M. | Huber, R. | Kloetzel, PM. | Poynor, M. | Schmidt, B. | Stein, M. | Central antiparallel beta-sheet flanked by helice | Cytosol | Hydrolase-hydrolase inhibitor complex | Inhibitor | Nucleus | Protease | Turnover of ubiquitinated substrate | Ubiquitin