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3d08
From Proteopedia
m (Protected "3d08" [edit=sysop:move=sysop]) |
Revision as of 08:41, 26 July 2012
Contents |
Human p53 core domain with hot spot mutation R249S and second-site suppressor mutation H168R
Template:ABSTRACT PUBMED 18996393
About this Structure
3d08 is a 1 chain structure of P53 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Suad O, Rozenberg H, Brosh R, Diskin-Posner Y, Kessler N, Shimon LJ, Frolow F, Liran A, Rotter V, Shakked Z. Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations. J Mol Biol. 2009 Jan 9;385(1):249-65. Epub 2008 Oct 30. PMID:18996393 doi:10.1016/j.jmb.2008.10.063
Categories: Homo sapiens | Frolow, F. | Rozenberg, H. | Shakked, Z. | Shimon, L J.W. | Suad, O. | Activator | Anti-oncogene | Apoptosis | Cell cycle | Covalent protein-rna linkage | Disease mutation | Dna-binding | Endoplasmic reticulum | Glycoprotein | Host-virus interaction | Li-fraumeni syndrome | Loop-sheet-helix motif | Metal-binding | Methylation | Mutant protein | Nucleus | P53 | Phosphoprotein | Transcription | Transcription regulation
