2bm2

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Template:STRUCTURE 2bm2

Contents

HUMAN BETA-II TRYPTASE IN COMPLEX WITH 4-(3-AMINOMETHYL-PHENYL)-PIPERIDIN-1-YL-(5-PHENETHYL- PYRIDIN-3-YL)-METHANONE

Template:ABSTRACT PUBMED 15781396

About this Structure

2bm2 is a 4 chain structure of Tryptase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Levell J, Astles P, Eastwood P, Cairns J, Houille O, Aldous S, Merriman G, Whiteley B, Pribish J, Czekaj M, Liang G, Maignan S, Guilloteau JP, Dupuy A, Davidson J, Harrison T, Morley A, Watson S, Fenton G, McCarthy C, Romano J, Mathew R, Engers D, Gardyan M, Sides K, Kwong J, Tsay J, Rebello S, Shen L, Wang J, Luo Y, Giardino O, Lim HK, Smith K, Pauls H. Structure based design of 4-(3-aminomethylphenyl)piperidinyl-1-amides: novel, potent, selective, and orally bioavailable inhibitors of betaII tryptase. Bioorg Med Chem. 2005 Apr 15;13(8):2859-72. PMID:15781396 doi:10.1016/j.bmc.2005.02.014

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