3mf5
From Proteopedia
(Difference between revisions)
m (Protected "3mf5" [edit=sysop:move=sysop]) |
|||
Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
- | [[3mf5]] is a 2 chain structure | + | [[3mf5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MF5 OCA]. |
==See Also== | ==See Also== |
Revision as of 13:10, 20 October 2012
Contents |
Hepatitis C virus polymerase NS5B (BK) with amide bioisostere thumb site inhibitor
Template:ABSTRACT PUBMED 20584604
About this Structure
3mf5 is a 2 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- Yang H, Hendricks RT, Arora N, Nitzan D, Yee C, Lucas MC, Yang Y, Fung A, Rajyaguru S, Harris SF, Leveque VJ, Hang JQ, Pogam SL, Reuter D, Tavares GA. Cyclic amide bioisosterism: strategic application to the design and synthesis of HCV NS5B polymerase inhibitors. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4614-9. Epub 2010 Jun 8. PMID:20584604 doi:10.1016/j.bmcl.2010.06.008