1e18

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[[Image:1e18.gif|left|200px]]<br /><applet load="1e18" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1e18.gif|left|200px]]
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caption="1e18, resolution 2.0&Aring;" />
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'''TUNGSTEN-SUSBSTITUTED DMSO REDUCTASE FROM RHODOBACTER CAPSULATUS'''<br />
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{{Structure
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|PDB= 1e18 |SIZE=350|CAPTION= <scene name='initialview01'>1e18</scene>, resolution 2.0&Aring;
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|SITE= <scene name='pdbsite=ACT:Active+Site'>ACT</scene>
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|LIGAND= <scene name='pdbligand=PGD:2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE+GUANOSINE+DINUCLEOTIDE'>PGD</scene>, <scene name='pdbligand=6WO:OXO-TUNGSTEN(VI)'>6WO</scene> and <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''TUNGSTEN-SUSBSTITUTED DMSO REDUCTASE FROM RHODOBACTER CAPSULATUS'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1E18 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rhodobacter_capsulatus Rhodobacter capsulatus] with <scene name='pdbligand=PGD:'>PGD</scene>, <scene name='pdbligand=6WO:'>6WO</scene> and <scene name='pdbligand=EOH:'>EOH</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Site: <scene name='pdbsite=ACT:Active+Site'>ACT</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E18 OCA].
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1E18 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rhodobacter_capsulatus Rhodobacter capsulatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E18 OCA].
==Reference==
==Reference==
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Dimethylsulfoxide reductase: an enzyme capable of catalysis with either molybdenum or tungsten at the active site., Stewart LJ, Bailey S, Bennett B, Charnock JM, Garner CD, McAlpine AS, J Mol Biol. 2000 Jun 9;299(3):593-600. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10835270 10835270]
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Dimethylsulfoxide reductase: an enzyme capable of catalysis with either molybdenum or tungsten at the active site., Stewart LJ, Bailey S, Bennett B, Charnock JM, Garner CD, McAlpine AS, J Mol Biol. 2000 Jun 9;299(3):593-600. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10835270 10835270]
[[Category: Rhodobacter capsulatus]]
[[Category: Rhodobacter capsulatus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tungsten]]
[[Category: tungsten]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:22:40 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:47:50 2008''

Revision as of 08:47, 20 March 2008

Image:1e18.gif


PDB ID 1e18

Drag the structure with the mouse to rotate
, resolution 2.0Å
Sites:
Ligands: , and
Coordinates: save as pdb, mmCIF, xml



TUNGSTEN-SUSBSTITUTED DMSO REDUCTASE FROM RHODOBACTER CAPSULATUS


Overview

DMSO reductase (DMSOR) from Rhodobacter capsulatus, well-characterised as a molybdoenzyme, will bind tungsten. Protein crystallography has shown that tungsten in W-DMSOR is ligated by the dithiolene group of the two pyranopterins, the oxygen atom of Ser147 plus another oxygen atom, and is located in a very similar site to that of molybdenum in Mo-DMSOR. These conclusions are consistent with W L(III)-edge X-ray absorption, EPR and UV/visible spectroscopic data. W-DMSOR is significantly more active than Mo-DMSOR in catalysing the reduction of DMSO but, in contrast to the latter, shows no significant ability to catalyse the oxidation of DMS.

About this Structure

1E18 is a Single protein structure of sequence from Rhodobacter capsulatus. Full crystallographic information is available from OCA.

Reference

Dimethylsulfoxide reductase: an enzyme capable of catalysis with either molybdenum or tungsten at the active site., Stewart LJ, Bailey S, Bennett B, Charnock JM, Garner CD, McAlpine AS, J Mol Biol. 2000 Jun 9;299(3):593-600. PMID:10835270

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