3ej1

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Revision as of 12:44, 26 July 2012

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Template:STRUCTURE 3ej1

Contents 1 CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor 2 About this Structure 3 See Also 4 Reference

CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor

Template:ABSTRACT PUBMED 18835709

About this Structure

3ej1 is a 4 chain structure of Cell Division Protein Kinase 2 and Cyclin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Cell Division Protein Kinase 2
• Cyclin

Reference

• Stevens KL, Reno MJ, Alberti JB, Price DJ, Kane-Carson LS, Knick VB, Shewchuk LM, Hassell AM, Veal JM, Davis ST, Griffin RJ, Peel MR. Synthesis and evaluation of pyrazolo[1,5-b]pyridazines as selective cyclin dependent kinase inhibitors. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5758-62. Epub 2008 Sep 24. PMID:18835709 doi:10.1016/j.bmcl.2008.09.069