3kga
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[3kga]] is a 1 chain structure | + | [[3kga]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KGA OCA]. |
==See Also== | ==See Also== | ||
Revision as of 13:49, 20 October 2012
Contents |
Crystal structure of MAPKAP kinase 2 (MK2) complexed with a potent 3-aminopyrazole ATP site inhibitor
Template:ABSTRACT PUBMED 20060294
About this Structure
3kga is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Velcicky J, Feifel R, Hawtin S, Heng R, Huppertz C, Koch G, Kroemer M, Moebitz H, Revesz L, Scheufler C, Schlapbach A. Novel 3-aminopyrazole inhibitors of MK-2 discovered by scaffold hopping strategy. Bioorg Med Chem Lett. 2010 Feb 1;20(3):1293-7. Epub 2009 Nov 3. PMID:20060294 doi:10.1016/j.bmcl.2009.10.138
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Be, C. | Huppertz, C. | Izaac, A. | Kroemer, M. | Pflieger, D. | Scheufler, C. | Schlapbach, A. | Velcicky, J. | 3-aminopyrazole scaffold | Activation loop deletion | Atp-binding | Atp-site kinase inhibitor | Induced fit | Kinase | Novel hydrophobic pocket | Nucleotide-binding | Phosphoprotein | Scaffold hoping | Serine/threonine-protein kinase | Small molecule inhibitor | Transferase
