1hvy
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[1hvy]] is a 4 chain structure of [[Thymidylate synthase] | + | [[1hvy]] is a 4 chain structure of [[Thymidylate synthase]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HVY OCA]. |
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:011329255</ref><references group="xtra"/> | <ref group="xtra">PMID:011329255</ref><references group="xtra"/> | ||
| - | [[Category: Homo sapiens]] | ||
[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
[[Category: Berger, S H.]] | [[Category: Berger, S H.]] | ||
Revision as of 06:16, 10 October 2012
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| 1hvy, resolution 1.90Å () | |||||||||
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| Ligands: | , , | ||||||||
| Non-Standard Residues: | |||||||||
| Activity: | Thymidylate synthase, with EC number 2.1.1.45 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Human thymidylate synthase complexed with dUMP and Raltitrexed, an antifolate drug, is in the closed conformation
Template:ABSTRACT PUBMED 11329255
About this Structure
1hvy is a 4 chain structure of Thymidylate synthase. Full crystallographic information is available from OCA.
See Also
Reference
- Phan J, Koli S, Minor W, Dunlap RB, Berger SH, Lebioda L. Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug. Biochemistry. 2001 Feb 20;40(7):1897-902. PMID:11329255
