2qmg

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Revision as of 14:31, 26 July 2012

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Template:STRUCTURE 2qmg

Contents 1 Structure of BACE Bound to SCH745966 2 About this Structure 3 See Also 4 Reference

Structure of BACE Bound to SCH745966

Template:ABSTRACT PUBMED 17980584

About this Structure

2qmg is a 2 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Iserloh U, Pan J, Stamford AW, Kennedy ME, Zhang Q, Zhang L, Parker EM, McHugh NA, Favreau L, Strickland C, Voigt J. Discovery of an orally efficaceous 4-phenoxypyrrolidine-based BACE-1 inhibitor. Bioorg Med Chem Lett. 2008 Jan 1;18(1):418-22. Epub 2007 Oct 18. PMID:17980584 doi:10.1016/j.bmcl.2007.10.053