1pyt
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[1pyt]] is a 4 chain structure | + | [[1pyt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PYT OCA]. |
==See Also== | ==See Also== | ||
Revision as of 15:01, 20 October 2012
Contents |
TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C
Template:ABSTRACT PUBMED 7556081
About this Structure
1pyt is a 4 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
See Also
Reference
- Gomis-Ruth FX, Gomez M, Bode W, Huber R, Aviles FX. The three-dimensional structure of the native ternary complex of bovine pancreatic procarboxypeptidase A with proproteinase E and chymotrypsinogen C. EMBO J. 1995 Sep 15;14(18):4387-94. PMID:7556081
- Gomis-Ruth FX, Gomez-Ortiz M, Vendrell J, Ventura S, Bode W, Huber R, Aviles FX. Crystal structure of an oligomer of proteolytic zymogens: detailed conformational analysis of the bovine ternary complex and implications for their activation. J Mol Biol. 1997 Jun 27;269(5):861-80. PMID:9223647 doi:S0022-2836(97)91040-8
- Rosendahl J, Witt H, Szmola R, Bhatia E, Ozsvari B, Landt O, Schulz HU, Gress TM, Pfutzer R, Lohr M, Kovacs P, Bluher M, Stumvoll M, Choudhuri G, Hegyi P, te Morsche RH, Drenth JP, Truninger K, Macek M Jr, Puhl G, Witt U, Schmidt H, Buning C, Ockenga J, Kage A, Groneberg DA, Nickel R, Berg T, Wiedenmann B, Bodeker H, Keim V, Mossner J, Teich N, Sahin-Toth M. Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis. Nat Genet. 2008 Jan;40(1):78-82. Epub 2007 Dec 2. PMID:18059268 doi:ng.2007.44
