This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2vuk
From Proteopedia
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2vuk]] is a 2 chain structure | + | [[2vuk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VUK OCA]. |
==See Also== | ==See Also== | ||
| Line 14: | Line 14: | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:018650397 | + | <ref group="xtra">PMID:018650397</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Boeckler, F M.]] | [[Category: Boeckler, F M.]] | ||
Revision as of 15:25, 20 October 2012
Contents |
STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO THE STABILIZING SMALL-MOLECULE DRUG PHIKAN083
Template:ABSTRACT PUBMED 18650397
About this Structure
2vuk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Boeckler FM, Joerger AC, Jaggi G, Rutherford TJ, Veprintsev DB, Fersht AR. Targeted rescue of a destabilized mutant of p53 by an in silico screened drug. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10360-5. Epub 2008 Jul 23. PMID:18650397
Categories: Homo sapiens | Boeckler, F M. | Fersht, A R. | Joerger, A C. | Activator | Anti-oncogene | Apoptosis | Cancer | Cell cycle | Covalent protein-rna linkage | Disease mutation | Dna binding | Dna-binding | Dna-binding protein | Endoplasmic reticulum | Glycoprotein | Host-virus interaction | Li-fraumeni syndrome | Metal binding | Metal-binding | Methylation | Nuclear protein | Nucleus | P53 dna- binding domain | Phosphoprotein | Protein stabilization | Second-site suppressor mutation | Small-molecule drug | Superstable mutant | Surface crevice | Transcription | Transcription regulation | Tumor suppressor | Virtual screening
