3ckp

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Revision as of 18:34, 26 July 2012

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Template:STRUCTURE 3ckp

Contents 1 Crystal structure of BACE-1 in complex with inhibitor 2 About this Structure 3 See Also 4 Reference

Crystal structure of BACE-1 in complex with inhibitor

Template:ABSTRACT PUBMED 18434152

About this Structure

3ckp is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Park H, Min K, Kwak HS, Koo KD, Lim D, Seo SW, Choi JU, Platt B, Choi DY. Synthesis, SAR, and X-ray structure of human BACE-1 inhibitors with cyclic urea derivatives. Bioorg Med Chem Lett. 2008 May 1;18(9):2900-4. Epub 2008 Apr 8. PMID:18434152 doi:10.1016/j.bmcl.2008.03.081