2qi8

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Revision as of 19:40, 26 July 2012

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Template:STRUCTURE 2qi8

Contents 1 Crystal structure of drug resistant SRC kinase domain 2 About this Structure 3 See Also 4 Reference

Crystal structure of drug resistant SRC kinase domain

Template:ABSTRACT PUBMED 18316192

About this Structure

2qi8 is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.

See Also

• Proto-oncogene tyrosine-protein kinase

Reference

• Michalczyk A, Kluter S, Rode HB, Simard JR, Grutter C, Rabiller M, Rauh D. Structural insights into how irreversible inhibitors can overcome drug resistance in EGFR. Bioorg Med Chem. 2008 Apr 1;16(7):3482-8. Epub 2008 Feb 20. PMID:18316192 doi:10.1016/j.bmc.2008.02.053