3edz
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[3edz]] is a 2 chain structure | + | [[3edz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EDZ OCA]. |
==See Also== | ==See Also== | ||
Revision as of 15:52, 20 October 2012
Contents |
Crystal structure of catalytic domain of TACE with hydroxamate inhibitor
Template:ABSTRACT PUBMED 18835710
About this Structure
3edz is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Mazzola RD Jr, Zhu Z, Sinning L, McKittrick B, Lavey B, Spitler J, Kozlowski J, Neng-Yang S, Zhou G, Guo Z, Orth P, Madison V, Sun J, Lundell D, Niu X. Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5809-14. Epub 2008 Sep 13. PMID:18835710 doi:10.1016/j.bmcl.2008.09.045
Categories: ADAM 17 endopeptidase | Homo sapiens | Guo, Z. | Kozlowski, J. | Lavey, B. | Lundell, D. | Madison, V. | Mazzola, R D. | McKittrick, B. | Neng-Yang, S. | Niu, X. | Orth, P. | Sinning, L. | Spitler, J. | Sun, J. | Zhou, G. | Zhu, Z. | Cleavage on pair of basic residue | Glycoprotein | Hydrolase | Membrane | Metal-binding | Metalloprotease | Notch signaling pathway | Phosphoprotein | Protease | Sh3-binding | Transmembrane | Zn-endopeptidase | Zymogen
