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3c09

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==About this Structure==
==About this Structure==
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[[3c09]] is a 6 chain structure of [[Epidermal Growth Factor Receptor]] and [[Monoclonal Antibody]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Homo_sapiens,_mus_musculus Homo sapiens, mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C09 OCA].
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[[3c09]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C09 OCA].
==See Also==
==See Also==
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<ref group="xtra">PMID:018394559</ref><references group="xtra"/>
<ref group="xtra">PMID:018394559</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Homo sapiens, mus musculus]]
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[[Category: Mus musculus]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Ferguson, K M.]]
[[Category: Ferguson, K M.]]

Revision as of 16:42, 20 October 2012

Template:STRUCTURE 3c09

Contents

Crystal structure the Fab fragment of matuzumab (Fab72000) in complex with domain III of the extracellular region of EGFR

Template:ABSTRACT PUBMED 18394559

About this Structure

3c09 is a 6 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

See Also

Reference

  • Schmiedel J, Blaukat A, Li S, Knochel T, Ferguson KM. Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization. Cancer Cell. 2008 Apr;13(4):365-73. PMID:18394559 doi:10.1016/j.ccr.2008.02.019

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