2qc8

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Revision as of 23:08, 26 July 2012

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spinqualitylabelsall models PDB ID 2qc8 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
2qc8, resolution 2.60Å ()
Ligands:	, , ,
Gene:	GLUL, GLNS (Homo sapiens)
Activity:	Glutamate--ammonia ligase, with EC number 6.3.1.2
Related:	2ojw
Structural annotation: Resources: InterPro : Ipr014746, Ipr008147, Ipr008146 Pfam : PF00120, PF03951 UniProt : P15104
Functional annotation: Cellular component: cytoplasm Biological process: nitrogen compound metabolic process glutamine biosynthetic process regulation of neurotransmitter levels Molecular function: ligase activity glutamate-ammonia ligase activity catalytic activity
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Contents 1 Crystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine phosphate 2 About this Structure 3 See Also 4 Reference

Crystal structure of human glutamine synthetase in complex with ADP and methionine sulfoximine phosphate

Template:ABSTRACT PUBMED 18005987

About this Structure

2qc8 is a 10 chain structure of Glutamine Synthase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Glutamine Synthase

Reference

• Krajewski WW, Collins R, Holmberg-Schiavone L, Jones TA, Karlberg T, Mowbray SL. Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design. J Mol Biol. 2008 Jan 4;375(1):217-28. Epub 2007 Oct 17. PMID:18005987 doi:10.1016/j.jmb.2007.10.029