2fz8

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Revision as of 00:44, 27 July 2012

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Template:STRUCTURE 2fz8

Contents 1 Human Aldose reductase complexed with inhibitor zopolrestat at 1.48 A(1 day soaking). 2 About this Structure 3 See Also 4 Reference

Human Aldose reductase complexed with inhibitor zopolrestat at 1.48 A(1 day soaking).

Template:ABSTRACT PUBMED 16952371

About this Structure

2fz8 is a 1 chain structure of Aldose Reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Aldose Reductase

Reference

• Steuber H, Zentgraf M, Gerlach C, Sotriffer CA, Heine A, Klebe G. Expect the unexpected or caveat for drug designers: multiple structure determinations using aldose reductase crystals treated under varying soaking and co-crystallisation conditions. J Mol Biol. 2006 Oct 13;363(1):174-87. Epub 2006 Aug 9. PMID:16952371 doi:http://dx.doi.org/10.1016/j.jmb.2006.08.011