3dv3

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Revision as of 02:23, 27 July 2012

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Template:STRUCTURE 3dv3

Contents 1 MEK1 with PF-04622664 Bound 2 About this Structure 3 See Also 4 Reference

MEK1 with PF-04622664 Bound

Template:ABSTRACT PUBMED 19019675

About this Structure

3dv3 is a 1 chain structure of Mitogen-activated protein kinase kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Mitogen-activated protein kinase kinase

Reference

• Tecle H, Shao J, Li Y, Kothe M, Kazmirski S, Penzotti J, Ding YH, Ohren J, Moshinsky D, Coli R, Jhawar N, Bora E, Jacques-O'Hagan S, Wu J. Beyond the MEK-pocket: can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK? Bioorg Med Chem Lett. 2009 Jan 1;19(1):226-9. Epub 2008 Oct 31. PMID:19019675 doi:10.1016/j.bmcl.2008.10.108