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3ovx

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Image:3ovx.png

Template:STRUCTURE 3ovx

Contents

Cathepsin S in complex with a covalent inhibitor with an aldehyde warhead

Template:ABSTRACT PUBMED 21030256

About this Structure

3ovx is a 2 chain structure of Cathepsin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Cai J, Robinson J, Belshaw S, Everett K, Fradera X, van Zeeland M, van Berkom L, van Rijnsbergen P, Popplestone L, Baugh M, Dempster M, Bruin J, Hamilton W, Kinghorn E, Westwood P, Kerr J, Rankovic Z, Arbuckle W, Bennett DJ, Jones PS, Long C, Martin I, Uitdehaag JC, Meulemans T. Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors. Bioorg Med Chem Lett. 2010 Dec 1;20(23):6890-4. Epub 2010 Oct 26. PMID:21030256 doi:10.1016/j.bmcl.2010.10.012

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OCA

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