3exo

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Revision as of 04:22, 27 July 2012

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Template:STRUCTURE 3exo

Contents 1 Crystal structure of BACE1 bound to inhibitor 2 About this Structure 3 See Also 4 Reference

Crystal structure of BACE1 bound to inhibitor

Template:ABSTRACT PUBMED 19036583

About this Structure

3exo is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Steele TG, Hills ID, Nomland AA, de Leon P, Allison T, McGaughey G, Colussi D, Tugusheva K, Haugabook SJ, Espeseth AS, Zuck P, Graham SL, Stachel SJ. Identification of a small molecule beta-secretase inhibitor that binds without catalytic aspartate engagement. Bioorg Med Chem Lett. 2009 Jan 1;19(1):17-20. Epub 2008 Nov 13. PMID:19036583 doi:10.1016/j.bmcl.2008.11.027