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3nww

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Revision as of 07:07, 27 July 2012

Image:3nww.png

Template:STRUCTURE 3nww

Contents

P38 Alpha kinase complexed with a 2-aminothiazol-5-yl-pyrimidine based inhibitor

Template:ABSTRACT PUBMED 20732813

About this Structure

3nww is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Lin S, Wrobleski ST, Hynes J Jr, Pitt S, Zhang R, Fan Y, Doweyko AM, Kish KF, Sack JS, Malley MF, Kiefer SE, Newitt JA, McKinnon M, Trzaskos J, Barrish JC, Dodd JH, Schieven GL, Leftheris K. Utilization of a nitrogen-sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38alpha MAP kinase inhibitors. Bioorg Med Chem Lett. 2010 Jul 30. PMID:20732813 doi:10.1016/j.bmcl.2010.07.102

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OCA

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