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3igv

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==About this Structure==
==About this Structure==
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[[3igv]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IGV OCA].
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[[3igv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IGV OCA].
==See Also==
==See Also==

Revision as of 19:46, 20 October 2012

Image:3igv.png

Template:STRUCTURE 3igv

Contents

Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydro-pyridinone inhibitor

Template:ABSTRACT PUBMED 19796938

About this Structure

3igv is a 2 chain structure with sequence from Viruses. Full crystallographic information is available from OCA.

See Also

Reference

  • Ellis DA, Blazel JK, Tran CV, Ruebsam F, Murphy DE, Li LS, Zhao J, Zhou Y, McGuire HM, Xiang AX, Webber SE, Zhao Q, Han Q, Kissinger CR, Lardy M, Gobbi A, Showalter RE, Shah AM, Tsan M, Patel RA, LeBrun LA, Kamran R, Bartkowski DM, Nolan TG, Norris DA, Sergeeva MV, Kirkovsky L. 5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6047-52. Epub 2009 Sep 17. PMID:19796938 doi:10.1016/j.bmcl.2009.09.051

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