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3f3w

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==About this Structure==
==About this Structure==
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[[3f3w]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F3W OCA].
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[[3f3w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F3W OCA].
==See Also==
==See Also==

Revision as of 20:00, 20 October 2012

Image:3f3w.png

Template:STRUCTURE 3f3w

Contents

Drug resistant cSrc kinase domain in complex with inhibitor RL45 (Type II)

Template:ABSTRACT PUBMED 19462975

About this Structure

3f3w is a 2 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.

See Also

Reference

  • Getlik M, Grutter C, Simard JR, Kluter S, Rabiller M, Rode HB, Robubi A, Rauh D. Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc. J Med Chem. 2009 Jul 9;52(13):3915-26. PMID:19462975 doi:10.1021/jm9002928

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