1acj
From Proteopedia
(Difference between revisions)
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1acj]] is a 1 chain structure | + | [[1acj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. The June 2004 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Acetylcholinesterase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2004_6 10.2210/rcsb_pdb/mom_2004_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ACJ OCA]. |
==See Also== | ==See Also== | ||
| Line 21: | Line 21: | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:008415649 | + | <ref group="xtra">PMID:008415649</ref><references group="xtra"/> |
[[Category: Acetylcholinesterase]] | [[Category: Acetylcholinesterase]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
Revision as of 20:23, 20 October 2012
| |||||||||
| 1acj, resolution 2.80Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | |||||||||
| Activity: | Acetylcholinesterase, with EC number 3.1.1.7 | ||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
QUATERNARY LIGAND BINDING TO AROMATIC RESIDUES IN THE ACTIVE-SITE GORGE OF ACETYLCHOLINESTERASE
Template:ABSTRACT PUBMED 8415649
About this Structure
1acj is a 1 chain structure with sequence from Torpedo californica. The June 2004 RCSB PDB Molecule of the Month feature on Acetylcholinesterase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2004_6. Full crystallographic information is available from OCA.
See Also
- AChE bivalent inhibitors
- AChE inhibitors and substrates
- AChE inhibitors and substrates (Part II)
- Acetylcholinesterase
- Acetylcholinesterase complexed with N-9-(1'%2C2'%2C3'%2C4'-tetrahydroacridinyl)-1%2C8-diaminooctane
- Torpedo Californica Acetylcholinesterase in complex with an (R)-Tacrine-(10)-Hupyridone inhibitor
- Torpedo californica acetylcholinesterase with alkylene-linked tacrine dimer (5 carbon linker)
- Torpedo californica acetylcholinesterase with alkylene-linked tacrine dimer (7 carbon linker)
Reference
- Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):9031-5. PMID:8415649
