1xkk
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[1xkk]] is a 1 chain structure | + | [[1xkk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The June 2010 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Epidermal Growth Factor Receptor'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2010_6 10.2210/rcsb_pdb/mom_2010_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKK OCA]. |
==See Also== | ==See Also== | ||
Revision as of 20:33, 20 October 2012
Contents |
EGFR kinase domain complexed with a quinazoline inhibitor- GW572016
Template:ABSTRACT PUBMED 15374980
About this Structure
1xkk is a 1 chain structure with sequence from Homo sapiens. The June 2010 RCSB PDB Molecule of the Month feature on Epidermal Growth Factor Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2010_6. Full crystallographic information is available from OCA.
See Also
Reference
- Wood ER, Truesdale AT, McDonald OB, Yuan D, Hassell A, Dickerson SH, Ellis B, Pennisi C, Horne E, Lackey K, Alligood KJ, Rusnak DW, Gilmer TM, Shewchuk L. A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells. Cancer Res. 2004 Sep 15;64(18):6652-9. PMID:15374980 doi:10.1158/0008-5472.CAN-04-1168
Categories: Epidermal Growth Factor Receptor | Homo sapiens | RCSB PDB Molecule of the Month | Transferase | Alligood, K J. | Dickerson, S H. | Ellis, B. | Gilmer, T M. | Hassell, A. | Horne, E. | Lackey, K. | McDonald, O B. | Pennisi, C. | Rusnak, D W. | Shewchuk, L M. | Truesdale, A T. | Wood, E R. | Yuan, D. | Egfr | Epidermal growth factor receptor | Kinase
