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1h3z

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[[Image:1h3z.jpg|left|200px]]<br /><applet load="1h3z" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1h3z.jpg|left|200px]]
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caption="1h3z" />
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'''SOLUTION STRUCTURE OF A PWWP DOMAIN FROM SCHIZOSACCHAROMYCES POMBE'''<br />
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{{Structure
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|PDB= 1h3z |SIZE=350|CAPTION= <scene name='initialview01'>1h3z</scene>
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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'''SOLUTION STRUCTURE OF A PWWP DOMAIN FROM SCHIZOSACCHAROMYCES POMBE'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1H3Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H3Z OCA].
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1H3Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H3Z OCA].
==Reference==
==Reference==
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Structural variation in PWWP domains., Slater LM, Allen MD, Bycroft M, J Mol Biol. 2003 Jul 11;330(3):571-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12842472 12842472]
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Structural variation in PWWP domains., Slater LM, Allen MD, Bycroft M, J Mol Biol. 2003 Jul 11;330(3):571-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12842472 12842472]
[[Category: Schizosaccharomyces pombe]]
[[Category: Schizosaccharomyces pombe]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: pwwp]]
[[Category: pwwp]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:57:10 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:31:52 2008''

Revision as of 09:31, 20 March 2008


PDB ID 1h3z

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SOLUTION STRUCTURE OF A PWWP DOMAIN FROM SCHIZOSACCHAROMYCES POMBE


Overview

The PWWP domain is a ubiquitous eukaryotic protein module characterised by a region of sequence similarity of approximately 80 amino acids containing a highly conserved PWWP motif. It is frequently found in proteins associated with chromatin. We have determined the structure of a PWWP domain from the S. pombe protein SPBC215.07c using NMR spectroscopy. The structure is composed of a five stranded beta barrel followed by two alpha helices. Comparison to the recently reported structure of a homologous domain from the mammalian DNA methyltransferase Dnmt3b reveals substantial differences both in the C-terminal helical region and in the PWWP motif.

About this Structure

1H3Z is a Single protein structure of sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.

Reference

Structural variation in PWWP domains., Slater LM, Allen MD, Bycroft M, J Mol Biol. 2003 Jul 11;330(3):571-6. PMID:12842472

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