1fkn
From Proteopedia
m (Protected "1fkn" [edit=sysop:move=sysop]) |
Revision as of 12:24, 27 July 2012
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| 1fkn, resolution 1.90Å () | |||||||||
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| Non-Standard Residues: | |||||||||
| Activity: | Memapsin 2, with EC number 3.4.23.46 | ||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
Contents |
Structure of Beta-Secretase Complexed with Inhibitor
Template:ABSTRACT PUBMED 11021803
About this Structure
1fkn is a 4 chain structure of Beta secretase with sequence from Homo sapiens. The July 2006 RCSB PDB Molecule of the Month feature on Amyloid-beta Precursor Protein by David S. Goodsell is 10.2210/rcsb_pdb/mom_2006_7. The July 2009 RCSB PDB Molecule of the Month feature on beta-Secretase by David Goodsell is 10.2210/rcsb_pdb/mom_2009_7. Full crystallographic information is available from OCA.
See Also
Reference
- Hong L, Koelsch G, Lin X, Wu S, Terzyan S, Ghosh AK, Zhang XC, Tang J. Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor. Science. 2000 Oct 6;290(5489):150-3. PMID:11021803
Categories: Amyloid-beta Precursor Protein | Homo sapiens | Memapsin 2 | RCSB PDB Molecule of the Month | Beta-Secretase | Ghosh, A. | Hong, L. | Koelsch, G. | Lin, X. | Tang, J. | Terzyan, S. | Wu, S. | Zhang, X C. | Alzheimer's disease | Aspartic protease | Base | Beta-secretase | Hydrolase-hydrolase inhibitor complex
