1kli
From Proteopedia
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Contents |
Cofactor-and substrate-assisted activation of factor VIIa
Template:ABSTRACT PUBMED 12225752
About this Structure
1kli is a 2 chain structure of Factor VIIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Sichler K, Banner DW, D'Arcy A, Hopfner KP, Huber R, Bode W, Kresse GB, Kopetzki E, Brandstetter H. Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions. J Mol Biol. 2002 Sep 20;322(3):591-603. PMID:12225752
- Dullweber F, Stubbs MT, Musil D, Sturzebecher J, Klebe G. Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J Mol Biol. 2001 Oct 26;313(3):593-614. PMID:11676542 doi:http://dx.doi.org/10.1006/jmbi.2001.5062
Categories: Coagulation factor VIIa | Homo sapiens | Arcy, A D. | Banner, D W. | Bode, W. | Brandstetter, H. | Hopfner, K P. | Huber, R. | Kopetzki, E. | Kresse, G B. | Sichler, K. | Extrinsic coagulation pathway | Hydrolase | Rational drug design | Serine protease activation | Substrate-assisted catalysis