3in3

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Revision as of 13:33, 27 July 2012

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Template:STRUCTURE 3in3

Contents 1 Bace1 with Compound 30 2 About this Structure 3 See Also 4 Reference

Bace1 with Compound 30

Template:ABSTRACT PUBMED 20045648

About this Structure

3in3 is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Malamas MS, Barnes K, Johnson M, Hui Y, Zhou P, Turner J, Hu Y, Wagner E, Fan K, Chopra R, Olland A, Bard J, Pangalos M, Reinhart P, Robichaud AJ. Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors. Bioorg Med Chem. 2010 Jan 15;18(2):630-9. Epub 2009 Dec 6. PMID:20045648 doi:10.1016/j.bmc.2009.12.007