1g5m

(Difference between revisions)

Revision as of 22:03, 20 October 2012

Related:

Structural annotation:
Resources:	CATH : 1G5Ma00 InterPro : Ipr004725, Ipr013278, Ipr003093, Ipr000712, Ipr002475, Ipr012238 Pfam : PF00452 SCOP : d1g5ma_ UniProt : P10415

Functional annotation:
Cellular component:	mitochondrial outer membrane membrane cytoplasm nucleus endoplasmic reticulum nuclear membrane mitochondrion cytosol integral to membrane
Biological process:	response to nicotine regulation of mitochondrial membrane potential pigmentation anti-apoptosis negative regulation of mitochondrial depolarization response to radiation regulation of mitochondrial membrane permeability regulation of protein homodimerization activity response to iron ion response to toxin female pregnancy regulation of protein heterodimerization activity hair follicle morphogenesis apoptosis positive regulation of cell proliferation regulation of apoptosis humoral immune response defense response to virus negative regulation of neuron apoptosis negative regulation of cellular pH reduction release of cytochrome c from mitochondria negative regulation of apoptosis neuron apoptosis regulation of viral genome replication
Molecular function:	protein heterodimerization activity identical protein binding protein binding protease binding protein homodimerization activity BH3 domain binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

1g5m is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Petros AM, Medek A, Nettesheim DG, Kim DH, Yoon HS, Swift K, Matayoshi ED, Oltersdorf T, Fesik SW. Solution structure of the antiapoptotic protein bcl-2. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3012-7. Epub 2001 Feb 27. PMID:11248023 doi:10.1073/pnas.041619798

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 ==About this Structure==
-[[1g5m]] is a 1 chain structure of [[Bcl-2]] and [[Horseradish peroxidase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G5M OCA].
+[[1g5m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G5M OCA].
 ==See Also==