1hmj
From Proteopedia
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| - | [[Image:1hmj.gif|left|200px]] | + | [[Image:1hmj.gif|left|200px]] |
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| - | '''SOLUTION STRUCTURE OF RNA POLYMERASE SUBUNIT H''' | + | {{Structure |
| + | |PDB= 1hmj |SIZE=350|CAPTION= <scene name='initialview01'>1hmj</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
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| + | '''SOLUTION STRUCTURE OF RNA POLYMERASE SUBUNIT H''' | ||
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==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1HMJ is a [ | + | 1HMJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HMJ OCA]. |
==Reference== | ==Reference== | ||
| - | RNA polymerase subunit H features a beta-ribbon motif within a novel fold that is present in archaea and eukaryotes., Thiru A, Hodach M, Eloranta JJ, Kostourou V, Weinzierl RO, Matthews S, J Mol Biol. 1999 Apr 9;287(4):753-60. PMID:[http:// | + | RNA polymerase subunit H features a beta-ribbon motif within a novel fold that is present in archaea and eukaryotes., Thiru A, Hodach M, Eloranta JJ, Kostourou V, Weinzierl RO, Matthews S, J Mol Biol. 1999 Apr 9;287(4):753-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10191143 10191143] |
[[Category: Methanocaldococcus jannaschii]] | [[Category: Methanocaldococcus jannaschii]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: subunit h]] | [[Category: subunit h]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:39:00 2008'' |
Revision as of 09:39, 20 March 2008
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SOLUTION STRUCTURE OF RNA POLYMERASE SUBUNIT H
Overview
The archaeal H and eukaryotic RPB5 RNA polymerase subunits are highly homologous and are likely to play a fundamental role in transcription that extends from archaea to humans. We report the structure of subunit H, in solution, from the archaeon Methanococcus jannaschii using multidimensional nuclear magnetic resonance. The structure reveals a novel fold containing a four-stranded mixed beta sheet that is flanked on one side by three short helices. The dominant feature is beta-ribbon motif, which presents a hydrophobic, basic surface, and defines a general RNA polymerase architectural scaffold.
About this Structure
1HMJ is a Single protein structure of sequence from Methanocaldococcus jannaschii. Full crystallographic information is available from OCA.
Reference
RNA polymerase subunit H features a beta-ribbon motif within a novel fold that is present in archaea and eukaryotes., Thiru A, Hodach M, Eloranta JJ, Kostourou V, Weinzierl RO, Matthews S, J Mol Biol. 1999 Apr 9;287(4):753-60. PMID:10191143
Page seeded by OCA on Thu Mar 20 11:39:00 2008
