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1huu

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[[Image:1huu.jpg|left|200px]]<br /><applet load="1huu" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1huu.jpg|left|200px]]
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caption="1huu, resolution 2.0&Aring;" />
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'''DNA-BINDING PROTEIN HU FROM BACILLUS STEAROTHERMOPHILUS'''<br />
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{{Structure
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|PDB= 1huu |SIZE=350|CAPTION= <scene name='initialview01'>1huu</scene>, resolution 2.0&Aring;
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|SITE=
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|LIGAND=
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|ACTIVITY=
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|GENE=
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}}
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'''DNA-BINDING PROTEIN HU FROM BACILLUS STEAROTHERMOPHILUS'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1HUU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HUU OCA].
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1HUU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HUU OCA].
==Reference==
==Reference==
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A protein structural motif that bends DNA., White SW, Appelt K, Wilson KS, Tanaka I, Proteins. 1989;5(4):281-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2508086 2508086]
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A protein structural motif that bends DNA., White SW, Appelt K, Wilson KS, Tanaka I, Proteins. 1989;5(4):281-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2508086 2508086]
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: minor groove binder]]
[[Category: minor groove binder]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:05:04 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:41:53 2008''

Revision as of 09:41, 20 March 2008


PDB ID 1huu

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, resolution 2.0Å
Coordinates: save as pdb, mmCIF, xml



DNA-BINDING PROTEIN HU FROM BACILLUS STEAROTHERMOPHILUS


Overview

The prokaryotic protein HU, integration host factor (IHF) from Escherichia coli, and transcription factor 1 (TF1) from bacteriophage SPO1 are closely related molecules. Biochemical results suggest that the role of these proteins is to bind and bend DNA. From the high-resolution structure of HU, we propose a model for this interaction with DNA. Crucial amino acid differences between the proteins can be rationalized in terms of their different specific functions.

About this Structure

1HUU is a Single protein structure of sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

A protein structural motif that bends DNA., White SW, Appelt K, Wilson KS, Tanaka I, Proteins. 1989;5(4):281-8. PMID:2508086

Page seeded by OCA on Thu Mar 20 11:41:53 2008

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