1hxb
From Proteopedia
(Difference between revisions)
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| - | [[Image:1hxb.gif|left|200px]] | + | [[Image:1hxb.gif|left|200px]] |
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| - | '''HIV-1 PROTEINASE COMPLEXED WITH RO 31-8959''' | + | {{Structure |
| + | |PDB= 1hxb |SIZE=350|CAPTION= <scene name='initialview01'>1hxb</scene>, resolution 2.30Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=QNC:2-CARBONYLQUINOLINE'>QNC</scene> and <scene name='pdbligand=DIQ:2-METHYL-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID'>DIQ</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] | ||
| + | |GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10239 Viruses]) | ||
| + | }} | ||
| + | |||
| + | '''HIV-1 PROTEINASE COMPLEXED WITH RO 31-8959''' | ||
| + | |||
==About this Structure== | ==About this Structure== | ||
| - | 1HXB is a [ | + | 1HXB is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. The following page contains interesting information on the relation of 1HXB with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb6_1.html HIV-1 Protease]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXB OCA]. |
==Reference== | ==Reference== | ||
| - | Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere., Krohn A, Redshaw S, Ritchie JC, Graves BJ, Hatada MH, J Med Chem. 1991 Nov;34(11):3340-2. PMID:[http:// | + | Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere., Krohn A, Redshaw S, Ritchie JC, Graves BJ, Hatada MH, J Med Chem. 1991 Nov;34(11):3340-2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1956054 1956054] |
[[Category: HIV-1 Protease]] | [[Category: HIV-1 Protease]] | ||
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
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[[Category: rna-directed dna polymerase]] | [[Category: rna-directed dna polymerase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:42:43 2008'' |
Revision as of 09:42, 20 March 2008
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| , resolution 2.30Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | and | ||||||
| Gene: | POL (Viruses) | ||||||
| Activity: | HIV-1 retropepsin, with EC number 3.4.23.16 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
HIV-1 PROTEINASE COMPLEXED WITH RO 31-8959
About this Structure
1HXB is a Single protein structure of sequence from Viruses. The following page contains interesting information on the relation of 1HXB with [HIV-1 Protease]. Full crystallographic information is available from OCA.
Reference
Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere., Krohn A, Redshaw S, Ritchie JC, Graves BJ, Hatada MH, J Med Chem. 1991 Nov;34(11):3340-2. PMID:1956054
Page seeded by OCA on Thu Mar 20 11:42:43 2008
