1iiu
From Proteopedia
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- | [[Image:1iiu.jpg|left|200px]] | + | [[Image:1iiu.jpg|left|200px]] |
- | + | ||
- | '''Chicken plasma retinol-binding protein (RBP)''' | + | {{Structure |
+ | |PDB= 1iiu |SIZE=350|CAPTION= <scene name='initialview01'>1iiu</scene>, resolution 2.50Å | ||
+ | |SITE= | ||
+ | |LIGAND= <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene> and <scene name='pdbligand=RTL:RETINOL'>RTL</scene> | ||
+ | |ACTIVITY= | ||
+ | |GENE= | ||
+ | }} | ||
+ | |||
+ | '''Chicken plasma retinol-binding protein (RBP)''' | ||
+ | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
- | 1IIU is a [ | + | 1IIU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IIU OCA]. |
==Reference== | ==Reference== | ||
- | Structure of chicken plasma retinol-binding protein., Zanotti G, Calderone V, Beda M, Malpeli G, Folli C, Berni R, Biochim Biophys Acta. 2001 Nov 26;1550(1):64-9. PMID:[http:// | + | Structure of chicken plasma retinol-binding protein., Zanotti G, Calderone V, Beda M, Malpeli G, Folli C, Berni R, Biochim Biophys Acta. 2001 Nov 26;1550(1):64-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11738088 11738088] |
[[Category: Gallus gallus]] | [[Category: Gallus gallus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: retinol]] | [[Category: retinol]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:50:58 2008'' |
Revision as of 09:51, 20 March 2008
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, resolution 2.50Å | |||||||
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Ligands: | and | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Chicken plasma retinol-binding protein (RBP)
Overview
The crystal structure of the specific carrier of retinol (retinol-binding protein, RBP) purified from chicken plasma has been determined (space group P2(1)2(1)2(1), with a=46.06(5) A, b=53.56(6) A, c=73.41(8) A, and one protein molecule in the asymmetric unit). Despite being obtained from a species phylogenetically distant from mammals, chicken holoRBP has an overall structure that closely resembles the previously determined structures of mammalian holoRBPs. The lack in chicken RBP of eight carboxy-terminal amino acid residues characteristic of mammalian RBPs does not significantly affect the protein structure. A distinctive feature of the avian protein is a better definition of the loop 63-67, close to the opening of the beta-barrel cavity accommodating the retinol molecule, which is rather disordered in the structures of mammalian RBPs.
About this Structure
1IIU is a Single protein structure of sequence from Gallus gallus. Full crystallographic information is available from OCA.
Reference
Structure of chicken plasma retinol-binding protein., Zanotti G, Calderone V, Beda M, Malpeli G, Folli C, Berni R, Biochim Biophys Acta. 2001 Nov 26;1550(1):64-9. PMID:11738088
Page seeded by OCA on Thu Mar 20 11:50:58 2008
Categories: Gallus gallus | Single protein | Berni, R. | Calderone, V. | Zanotti, G. | CD | RTL | Rbp | Retinol