1in0
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:1in0.jpg|left|200px]] | + | [[Image:1in0.jpg|left|200px]] |
| - | + | ||
| - | '''YAJQ PROTEIN (HI1034)''' | + | {{Structure |
| + | |PDB= 1in0 |SIZE=350|CAPTION= <scene name='initialview01'>1in0</scene>, resolution 2.14Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=MMC:METHYL MERCURY ION'>MMC</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= yajQ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae]) | ||
| + | }} | ||
| + | |||
| + | '''YAJQ PROTEIN (HI1034)''' | ||
| + | |||
==Overview== | ==Overview== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1IN0 is a [ | + | 1IN0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IN0 OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structure of the YajQ protein from Haemophilus influenzae reveals a tandem of RNP-like domains., Teplyakov A, Obmolova G, Bir N, Reddy P, Howard AJ, Gilliland GL, J Struct Funct Genomics. 2003;4(1):1-9. PMID:[http:// | + | Crystal structure of the YajQ protein from Haemophilus influenzae reveals a tandem of RNP-like domains., Teplyakov A, Obmolova G, Bir N, Reddy P, Howard AJ, Gilliland GL, J Struct Funct Genomics. 2003;4(1):1-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12943362 12943362] |
[[Category: Haemophilus influenzae]] | [[Category: Haemophilus influenzae]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| Line 21: | Line 30: | ||
[[Category: alpha and beta sandwich]] | [[Category: alpha and beta sandwich]] | ||
[[Category: s2f]] | [[Category: s2f]] | ||
| - | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: structure 2 function project]] | [[Category: structure 2 function project]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:52:30 2008'' |
Revision as of 09:52, 20 March 2008
| |||||||
| , resolution 2.14Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | , and | ||||||
| Gene: | yajQ (Haemophilus influenzae) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
YAJQ PROTEIN (HI1034)
Overview
A hypothetical protein encoded by the gene YajQ of Haemophilus influenzae was selected, as part of a structural genomics project, for X-ray crystallographic structure determination and analysis to assist with the functional assignment. The protein is present in most bacteria, but not in archaea or eukaryotes. The amino acid sequence has no homology to that of other proteins. The YajQ protein was cloned, expressed, and the crystal structure determined at 2.1-A resolution by applying the multiwavelength anomalous dispersion method to a mercury derivative. The polypeptide chain is folded into two domains with identical folding topology. Each domain has a four-stranded antiparallel beta-sheet flanked on one side by two alpha-helices. This structural motif is a characteristic feature of many RNA-binding proteins. The tetrameric structure observed in the crystal suggests a possibility of binding two stretches of double-stranded nucleic acid.
About this Structure
1IN0 is a Single protein structure of sequence from Haemophilus influenzae. Full crystallographic information is available from OCA.
Reference
Crystal structure of the YajQ protein from Haemophilus influenzae reveals a tandem of RNP-like domains., Teplyakov A, Obmolova G, Bir N, Reddy P, Howard AJ, Gilliland GL, J Struct Funct Genomics. 2003;4(1):1-9. PMID:12943362
Page seeded by OCA on Thu Mar 20 11:52:30 2008
