1tge

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1tge" [edit=sysop:move=sysop])
Line 1: Line 1:
-
[[Image:1tge.png|left|200px]]
+
==The structure of immature Dengue virus at 12.5 angstrom==
 +
<StructureSection load='1tge' size='340' side='right' caption='[[1tge]], [[Resolution|resolution]] 12.50&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1tge]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_2_puerto_rico/pr159-s1/1969 Dengue virus 2 puerto rico/pr159-s1/1969]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TGE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TGE FirstGlance]. <br>
 +
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tg8|1tg8]], [[1thd|1thd]]</td></tr>
 +
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tge FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tge OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1tge RCSB], [http://www.ebi.ac.uk/pdbsum/1tge PDBsum]</span></td></tr>
 +
<table>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Dengue virus, a member of the Flaviviridae family, has a surface composed of 180 copies each of the envelope (E) glycoprotein and the membrane (M) protein. The crystal structure of an N-terminal fragment of E has been determined and compared with a previously described structure. The primary difference between these structures is a 10 degrees rotation about a hinge relating the fusion domain DII to domains DI and DIII. These two rigid body components were used for independent fitting of E into the cryo-electron microscopy maps of both immature and mature dengue viruses. The fitted E structures in these two particles showed a difference of 27 degrees between the two components. Comparison of the E structure in its postfusion state with that in the immature and mature virions shows a rotation approximately around the same hinge. Flexibility of E is apparently a functional requirement for assembly and infection of flaviviruses.
-
{{STRUCTURE_1tge| PDB=1tge | SCENE= }}
+
Conformational changes of the flavivirus E glycoprotein.,Zhang Y, Zhang W, Ogata S, Clements D, Strauss JH, Baker TS, Kuhn RJ, Rossmann MG Structure. 2004 Sep;12(9):1607-18. PMID:15341726<ref>PMID:15341726</ref>
-
===The structure of immature Dengue virus at 12.5 angstrom===
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
 
+
</div>
-
{{ABSTRACT_PUBMED_15341726}}
+
== References ==
-
 
+
<references/>
-
==About this Structure==
+
__TOC__
-
[[1tge]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TGE OCA].
+
</StructureSection>
-
 
+
[[Category: Dengue virus 2 puerto rico/pr159-s1/1969]]
-
==Reference==
+
-
<ref group="xtra">PMID:015341726</ref><references group="xtra"/>
+
-
[[Category: Viruses]]
+
[[Category: Baker, T S.]]
[[Category: Baker, T S.]]
[[Category: Clements, D.]]
[[Category: Clements, D.]]

Revision as of 06:46, 9 June 2014

The structure of immature Dengue virus at 12.5 angstrom

1tge, resolution 12.50Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1tge"
Views
Personal tools
Navigation
Toolbox