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127d

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Revision as of 18:59, 14 August 2012

Image:127d.png

Template:STRUCTURE 127d

DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') COMPLEXED WITH HOECHST 33258

Template:ABSTRACT PUBMED 1371249

About this Structure

127d is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Sriram M, van der Marel GA, Roelen HL, van Boom JH, Wang AH. Conformation of B-DNA containing O6-ethyl-G-C base pairs stabilized by minor groove binding drugs: molecular structure of d(CGC[e6G]AATTCGCG complexed with Hoechst 33258 or Hoechst 33342. EMBO J. 1992 Jan;11(1):225-32. PMID:1371249
  • Yasui LS, Chen K, Wang K, Jones TP, Caldwell J, Guse D, Kassis AI. Using Hoechst 33342 to target radioactivity to the cell nucleus. Radiat Res. 2007 Feb;167(2):167-75. PMID:17390724

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OCA

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