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4ezt

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'''Unreleased structure'''
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{{STRUCTURE_4ezt| PDB=4ezt | SCENE= }}
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===Crystal structure of the substrate binding domain of E.coli DnaK in complex with heliocin (residues 14 to 21)===
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{{ABSTRACT_PUBMED_23562829}}
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The entry 4ezt is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]
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Authors: Zahn, M., Straeter, N.
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==About this Structure==
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[[4ezt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZT OCA].
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Description: Crystal structure of the substrate binding domain of E.coli DnaK in complex with heliocin (residues 14 to 21)
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[[Category: Escherichia coli k-12]]
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[[Category: Straeter, N.]]
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[[Category: Zahn, M.]]
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[[Category: Chaperone]]
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[[Category: Chaperone-peptide binding protein complex]]
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[[Category: Peptide binding]]

Revision as of 20:28, 17 April 2013

Template:STRUCTURE 4ezt

Crystal structure of the substrate binding domain of E.coli DnaK in complex with heliocin (residues 14 to 21)

Template:ABSTRACT PUBMED 23562829

Function

[DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332]

About this Structure

4ezt is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

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