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3ssu

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[[Image:3ssu.jpg|left|200px]]
 
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{{STRUCTURE_3ssu| PDB=3ssu | SCENE= }}
{{STRUCTURE_3ssu| PDB=3ssu | SCENE= }}
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===Crystal structure of vimentin coil1A/1B fragment===
===Crystal structure of vimentin coil1A/1B fragment===
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{{ABSTRACT_PUBMED_22869704}}
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==Function==
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[[http://www.uniprot.org/uniprot/VIME_HUMAN VIME_HUMAN]] Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.<ref>PMID:21746880</ref> Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.<ref>PMID:21746880</ref>
==About this Structure==
==About this Structure==
[[3ssu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSU OCA].
[[3ssu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSU OCA].
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==Reference==
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<ref group="xtra">PMID:022869704</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chernyatina, A A.]]
[[Category: Chernyatina, A A.]]

Revision as of 10:12, 3 July 2013

Template:STRUCTURE 3ssu

Contents

Crystal structure of vimentin coil1A/1B fragment

Template:ABSTRACT PUBMED 22869704

Function

[VIME_HUMAN] Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.[1] Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.[2]

About this Structure

3ssu is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Chernyatina AA, Nicolet S, Aebi U, Herrmann H, Strelkov SV. Atomic structure of the vimentin central alpha-helical domain and its implications for intermediate filament assembly. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13620-5. doi:, 10.1073/pnas.1206836109. Epub 2012 Aug 6. PMID:22869704 doi:10.1073/pnas.1206836109
  1. ↑ Challa AA, Stefanovic B. A novel role of vimentin filaments: binding and stabilization of collagen mRNAs. Mol Cell Biol. 2011 Sep;31(18):3773-89. doi: 10.1128/MCB.05263-11. Epub 2011 Jul , 11. PMID:21746880 doi:10.1128/MCB.05263-11
  2. ↑ Challa AA, Stefanovic B. A novel role of vimentin filaments: binding and stabilization of collagen mRNAs. Mol Cell Biol. 2011 Sep;31(18):3773-89. doi: 10.1128/MCB.05263-11. Epub 2011 Jul , 11. PMID:21746880 doi:10.1128/MCB.05263-11

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