3swk
From Proteopedia
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{{STRUCTURE_3swk| PDB=3swk | SCENE= }} | {{STRUCTURE_3swk| PDB=3swk | SCENE= }} | ||
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===Crystal structure of vimentin coil1B fragment=== | ===Crystal structure of vimentin coil1B fragment=== | ||
| + | {{ABSTRACT_PUBMED_22869704}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/VIME_HUMAN VIME_HUMAN]] Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.<ref>PMID:21746880</ref> Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.<ref>PMID:21746880</ref> | ||
==About this Structure== | ==About this Structure== | ||
[[3swk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SWK OCA]. | [[3swk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SWK OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022869704</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Chernyatina, A A.]] | [[Category: Chernyatina, A A.]] | ||
Revision as of 12:08, 3 July 2013
Contents |
Crystal structure of vimentin coil1B fragment
Template:ABSTRACT PUBMED 22869704
Function
[VIME_HUMAN] Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.[1] Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.[2]
About this Structure
3swk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Chernyatina AA, Nicolet S, Aebi U, Herrmann H, Strelkov SV. Atomic structure of the vimentin central alpha-helical domain and its implications for intermediate filament assembly. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13620-5. doi:, 10.1073/pnas.1206836109. Epub 2012 Aug 6. PMID:22869704 doi:10.1073/pnas.1206836109
- ↑ Challa AA, Stefanovic B. A novel role of vimentin filaments: binding and stabilization of collagen mRNAs. Mol Cell Biol. 2011 Sep;31(18):3773-89. doi: 10.1128/MCB.05263-11. Epub 2011 Jul , 11. PMID:21746880 doi:10.1128/MCB.05263-11
- ↑ Challa AA, Stefanovic B. A novel role of vimentin filaments: binding and stabilization of collagen mRNAs. Mol Cell Biol. 2011 Sep;31(18):3773-89. doi: 10.1128/MCB.05263-11. Epub 2011 Jul , 11. PMID:21746880 doi:10.1128/MCB.05263-11
