G09SecL04Tpc2

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<Structure load='1fj1' size='300' frame='true' align='right' caption='Outer Surface Protein A Dimer With LA-2 Complex' scene='G09SecL04Tpc2/1' />
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<StructureSection load='1FJ1' size='350' side='right' caption='Structure of OspA (PDB entry [[FJ1]])' scene=''>
'''Outer Surface Protein A (OspA)''' is a major [http://en.wikipedia.org/wiki/Lipoprotein lipoprotein] on the ''borrelia burgdorferi'' [http://en.wikipedia.org/wiki/Spirochete spirochete] which is a causative agent of Lyme Disease. The three loops in the C-terminus define the OspA antigen-antibody complex. The interaction between the loops and the LA-2 (antibody) forms the basis for OspA vaccination. Along with other surface proteins, OspA has many important functions that are associated with [http://en.wikipedia.org/wiki/Lyme_Disease Lyme Disease] such as late stage neurological disorders including acute Lyme [http://en.wikipedia.org/wiki/Neuroborreliosis Neuroborreliosis].
'''Outer Surface Protein A (OspA)''' is a major [http://en.wikipedia.org/wiki/Lipoprotein lipoprotein] on the ''borrelia burgdorferi'' [http://en.wikipedia.org/wiki/Spirochete spirochete] which is a causative agent of Lyme Disease. The three loops in the C-terminus define the OspA antigen-antibody complex. The interaction between the loops and the LA-2 (antibody) forms the basis for OspA vaccination. Along with other surface proteins, OspA has many important functions that are associated with [http://en.wikipedia.org/wiki/Lyme_Disease Lyme Disease] such as late stage neurological disorders including acute Lyme [http://en.wikipedia.org/wiki/Neuroborreliosis Neuroborreliosis].

Revision as of 07:16, 21 August 2012

Structure of OspA (PDB entry FJ1)

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Albert Kurian, Nabil Faridi, Michal Harel, Amar Patole

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