4dea

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Revision as of 05:27, 12 September 2012

Template:STRUCTURE 4dea

Aurora A in complex with YL1-038-18

Template:ABSTRACT PUBMED 22803810

About this Structure

4dea is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Lawrence H, Martin MP, Luo Y, Pireddu R, Yang H, Gevariya H, Ozcan S, Zhu JY, Kendig R, Rodriguez M, Elias R, Cheng J, Sebti SM, Schonbrunn E, Lawrence NJ. Development of ortho-Chlorophenyl Substituted Pyrimidines as Exceptionally Potent Aurora A Inhibitors. J Med Chem. 2012 Jul 17. PMID:22803810 doi:10.1021/jm300334d