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4gh8
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4gh8| PDB=4gh8 | SCENE= }} | |
| + | ===Crystal structure of a 'humanized' E. coli dihydrofolate reductase=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | ||
| - | + | ==About this Structure== | |
| - | + | [[4gh8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GH8 OCA]. | |
| - | + | [[Category: Dihydrofolate reductase]] | |
| + | [[Category: Escherichia coli k-12]] | ||
| + | [[Category: Benkovic, S J.]] | ||
| + | [[Category: French, J B.]] | ||
| + | [[Category: Hammes-Schiffer, S.]] | ||
| + | [[Category: Hanoian, P.]] | ||
| + | [[Category: Liu, C T.]] | ||
| + | [[Category: Pringle, T H.]] | ||
| + | [[Category: Dihydrofolate reductase]] | ||
| + | [[Category: Enzyme catalysis]] | ||
| + | [[Category: Evolution]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Tetrahydrofolate]] | ||
Revision as of 18:13, 19 June 2013
Crystal structure of a 'humanized' E. coli dihydrofolate reductase
Function
[DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
About this Structure
4gh8 is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
