1jdq
From Proteopedia
Line 1: | Line 1: | ||
- | [[Image:1jdq.jpg|left|200px]] | + | [[Image:1jdq.jpg|left|200px]] |
- | + | ||
- | '''Solution Structure of TM006 Protein from Thermotoga maritima''' | + | {{Structure |
+ | |PDB= 1jdq |SIZE=350|CAPTION= <scene name='initialview01'>1jdq</scene> | ||
+ | |SITE= | ||
+ | |LIGAND= | ||
+ | |ACTIVITY= | ||
+ | |GENE= | ||
+ | }} | ||
+ | |||
+ | '''Solution Structure of TM006 Protein from Thermotoga maritima''' | ||
+ | |||
==Overview== | ==Overview== | ||
Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
- | 1JDQ is a [ | + | 1JDQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JDQ OCA]. |
==Reference== | ==Reference== | ||
- | An NMR approach to structural proteomics., Yee A, Chang X, Pineda-Lucena A, Wu B, Semesi A, Le B, Ramelot T, Lee GM, Bhattacharyya S, Gutierrez P, Denisov A, Lee CH, Cort JR, Kozlov G, Liao J, Finak G, Chen L, Wishart D, Lee W, McIntosh LP, Gehring K, Kennedy MA, Edwards AM, Arrowsmith CH, Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1825-30. PMID:[http:// | + | An NMR approach to structural proteomics., Yee A, Chang X, Pineda-Lucena A, Wu B, Semesi A, Le B, Ramelot T, Lee GM, Bhattacharyya S, Gutierrez P, Denisov A, Lee CH, Cort JR, Kozlov G, Liao J, Finak G, Chen L, Wishart D, Lee W, McIntosh LP, Gehring K, Kennedy MA, Edwards AM, Arrowsmith CH, Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1825-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11854485 11854485] |
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Thermotoga maritima]] | [[Category: Thermotoga maritima]] | ||
Line 19: | Line 28: | ||
[[Category: Kozlov, G.]] | [[Category: Kozlov, G.]] | ||
[[Category: Yee, A.]] | [[Category: Yee, A.]] | ||
- | [[Category: structural | + | [[Category: structural genomic]] |
[[Category: thermotoga maritima]] | [[Category: thermotoga maritima]] | ||
[[Category: tm006]] | [[Category: tm006]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:02:02 2008'' |
Revision as of 10:02, 20 March 2008
| |||||||
Coordinates: | save as pdb, mmCIF, xml |
Solution Structure of TM006 Protein from Thermotoga maritima
Overview
The influx of genomic sequence information has led to the concept of structural proteomics, the determination of protein structures on a genome-wide scale. Here we describe an approach to structural proteomics of small proteins using NMR spectroscopy. Over 500 small proteins from several organisms were cloned, expressed, purified, and evaluated by NMR. Although there was variability among proteomes, overall 20% of these proteins were found to be readily amenable to NMR structure determination. NMR sample preparation was centralized in one facility, and a distributive approach was used for NMR data collection and analysis. Twelve structures are reported here as part of this approach, which allowed us to infer putative functions for several conserved hypothetical proteins.
About this Structure
1JDQ is a Single protein structure of sequence from Thermotoga maritima. Full crystallographic information is available from OCA.
Reference
An NMR approach to structural proteomics., Yee A, Chang X, Pineda-Lucena A, Wu B, Semesi A, Le B, Ramelot T, Lee GM, Bhattacharyya S, Gutierrez P, Denisov A, Lee CH, Cort JR, Kozlov G, Liao J, Finak G, Chen L, Wishart D, Lee W, McIntosh LP, Gehring K, Kennedy MA, Edwards AM, Arrowsmith CH, Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1825-30. PMID:11854485
Page seeded by OCA on Thu Mar 20 12:02:02 2008