1jjw
From Proteopedia
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- | [[Image:1jjw.gif|left|200px]] | + | [[Image:1jjw.gif|left|200px]] |
- | + | ||
- | '''Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution''' | + | {{Structure |
+ | |PDB= 1jjw |SIZE=350|CAPTION= <scene name='initialview01'>1jjw</scene>, resolution 1.90Å | ||
+ | |SITE= | ||
+ | |LIGAND= <scene name='pdbligand=K:POTASSIUM ION'>K</scene> | ||
+ | |ACTIVITY= | ||
+ | |GENE= HslV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae]) | ||
+ | }} | ||
+ | |||
+ | '''Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution''' | ||
+ | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
- | 1JJW is a [ | + | 1JJW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJW OCA]. |
==Reference== | ==Reference== | ||
- | Structure of Haemophilus influenzae HslV protein at 1.9 A resolution, revealing a cation-binding site near the catalytic site., Sousa MC, McKay DB, Acta Crystallogr D Biol Crystallogr. 2001 Dec;57(Pt 12):1950-4. Epub 2001, Nov 21. PMID:[http:// | + | Structure of Haemophilus influenzae HslV protein at 1.9 A resolution, revealing a cation-binding site near the catalytic site., Sousa MC, McKay DB, Acta Crystallogr D Biol Crystallogr. 2001 Dec;57(Pt 12):1950-4. Epub 2001, Nov 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11717526 11717526] |
[[Category: Haemophilus influenzae]] | [[Category: Haemophilus influenzae]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: quasi-equivalent packing]] | [[Category: quasi-equivalent packing]] | ||
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:04:25 2008'' |
Revision as of 10:04, 20 March 2008
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, resolution 1.90Å | |||||||
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Ligands: | |||||||
Gene: | HslV (Haemophilus influenzae) | ||||||
Coordinates: | save as pdb, mmCIF, xml |
Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution
Overview
The structure of the Haemophilus influenzae HslV protease of the HslUV 'prokaryotic proteasome' has been solved by molecular replacement and refined with data to 1.9 A resolution. The protease is a 'double donut' of hexameric rings; two alternative sets of intermolecular interactions between protomers in the rings result in 'quasi-equivalent' packing within the assembly. Anomalous scattering data from crystals with potassium present in the mother liquor reveal a K(+) ion bound with octahedral coordination near the active-site Thr1 residue. The site also binds Na(+) ions and is likely to bind Mg(2+), suggesting that monovalent and divalent metal ions may influence the catalytic activity of the protease.
About this Structure
1JJW is a Single protein structure of sequence from Haemophilus influenzae. Full crystallographic information is available from OCA.
Reference
Structure of Haemophilus influenzae HslV protein at 1.9 A resolution, revealing a cation-binding site near the catalytic site., Sousa MC, McKay DB, Acta Crystallogr D Biol Crystallogr. 2001 Dec;57(Pt 12):1950-4. Epub 2001, Nov 21. PMID:11717526
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