1jjw

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[[Image:1jjw.gif|left|200px]]<br /><applet load="1jjw" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1jjw.gif|left|200px]]
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caption="1jjw, resolution 1.90&Aring;" />
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'''Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution'''<br />
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{{Structure
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|PDB= 1jjw |SIZE=350|CAPTION= <scene name='initialview01'>1jjw</scene>, resolution 1.90&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=K:POTASSIUM ION'>K</scene>
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|ACTIVITY=
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|GENE= HslV ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae])
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}}
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'''Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1JJW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae] with <scene name='pdbligand=K:'>K</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJW OCA].
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1JJW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JJW OCA].
==Reference==
==Reference==
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Structure of Haemophilus influenzae HslV protein at 1.9 A resolution, revealing a cation-binding site near the catalytic site., Sousa MC, McKay DB, Acta Crystallogr D Biol Crystallogr. 2001 Dec;57(Pt 12):1950-4. Epub 2001, Nov 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11717526 11717526]
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Structure of Haemophilus influenzae HslV protein at 1.9 A resolution, revealing a cation-binding site near the catalytic site., Sousa MC, McKay DB, Acta Crystallogr D Biol Crystallogr. 2001 Dec;57(Pt 12):1950-4. Epub 2001, Nov 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11717526 11717526]
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: quasi-equivalent packing]]
[[Category: quasi-equivalent packing]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:23:30 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:04:25 2008''

Revision as of 10:04, 20 March 2008


PDB ID 1jjw

Drag the structure with the mouse to rotate
, resolution 1.90Å
Ligands:
Gene: HslV (Haemophilus influenzae)
Coordinates: save as pdb, mmCIF, xml



Structure of Haemophilus influenzae HslV Protein at 1.9 A Resolution


Overview

The structure of the Haemophilus influenzae HslV protease of the HslUV 'prokaryotic proteasome' has been solved by molecular replacement and refined with data to 1.9 A resolution. The protease is a 'double donut' of hexameric rings; two alternative sets of intermolecular interactions between protomers in the rings result in 'quasi-equivalent' packing within the assembly. Anomalous scattering data from crystals with potassium present in the mother liquor reveal a K(+) ion bound with octahedral coordination near the active-site Thr1 residue. The site also binds Na(+) ions and is likely to bind Mg(2+), suggesting that monovalent and divalent metal ions may influence the catalytic activity of the protease.

About this Structure

1JJW is a Single protein structure of sequence from Haemophilus influenzae. Full crystallographic information is available from OCA.

Reference

Structure of Haemophilus influenzae HslV protein at 1.9 A resolution, revealing a cation-binding site near the catalytic site., Sousa MC, McKay DB, Acta Crystallogr D Biol Crystallogr. 2001 Dec;57(Pt 12):1950-4. Epub 2001, Nov 21. PMID:11717526

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