4ggh

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[[Image:4ggh.jpg|left|200px]]
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==Crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, hepes, and ethylene glycol bound (ordered loops, space group c2221)==
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<StructureSection load='4ggh' size='340' side='right' caption='[[4ggh]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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{{STRUCTURE_4ggh| PDB=4ggh | SCENE= }}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ggh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_harveyi Vibrio harveyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GGH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GGH FirstGlance]. <br>
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===Crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, hepes, and ethylene glycol bound (ordered loops, space group c2221)===
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VME_00770 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=669 Vibrio harveyi])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ggh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ggh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ggh RCSB], [http://www.ebi.ac.uk/pdbsum/4ggh PDBsum]</span></td></tr>
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==About this Structure==
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</table>
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[[4ggh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_harveyi Vibrio harveyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GGH OCA].
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== Function ==
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[[http://www.uniprot.org/uniprot/D0X4R4_VIBHA D0X4R4_VIBHA]] Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.<ref>PMID:24697546</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Vibrio harveyi]]
[[Category: Vibrio harveyi]]
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[[Category: Almo, S C.]]
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[[Category: Almo, S C]]
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[[Category: Bhosle, R.]]
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[[Category: Bhosle, R]]
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[[Category: Chowdhury, S.]]
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[[Category: Chowdhury, S]]
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[[Category: EFI, Enzyme Function Initiative.]]
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[[Category: EFI, Enzyme Function Initiative]]
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[[Category: Evans, B.]]
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[[Category: Evans, B]]
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[[Category: Gerlt, J A.]]
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[[Category: Gerlt, J A]]
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[[Category: Glenn, A Scott.]]
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[[Category: Glenn, A Scott]]
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[[Category: Hammonds, J.]]
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[[Category: Hammonds, J]]
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[[Category: Hillerich, B.]]
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[[Category: Hillerich, B]]
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[[Category: Imker, H J.]]
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[[Category: Imker, H J]]
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[[Category: Love, J.]]
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[[Category: Love, J]]
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[[Category: Morisco, L L.]]
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[[Category: Morisco, L L]]
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[[Category: Obaidi, N F.Al.]]
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[[Category: Obaidi, N F.Al]]
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[[Category: Seidel, R D.]]
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[[Category: Seidel, R D]]
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[[Category: Sojitra, S.]]
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[[Category: Sojitra, S]]
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[[Category: Toro, R.]]
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[[Category: Toro, R]]
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[[Category: Vetting, M W.]]
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[[Category: Vetting, M W]]
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[[Category: Washington, E.]]
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[[Category: Washington, E]]
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[[Category: Wasserman, S R.]]
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[[Category: Wasserman, S R]]
[[Category: Efi]]
[[Category: Efi]]
[[Category: Enolase]]
[[Category: Enolase]]

Revision as of 13:10, 4 January 2015

Crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, hepes, and ethylene glycol bound (ordered loops, space group c2221)

4ggh, resolution 1.90Å

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