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Nuclear receptor

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(New page: == Nuclear Receptor == === Structure === ==== DBD (DNA Binding Domain) ==== ==== LBD (Ligand Binding Domain) ==== <StructureSection load='1ie8' size='350' side='right' caption='Structure ...)
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==== DBD (DNA Binding Domain) ====
==== DBD (DNA Binding Domain) ====
==== LBD (Ligand Binding Domain) ====
==== LBD (Ligand Binding Domain) ====
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<StructureSection load='1ie8' size='350' side='right' caption='Structure of HMG-CoA reductase (PDB entry [[1ie8]])' scene=''>
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<StructureSection load='1ie8' size='350' side='right' caption='Structure of the LBD of a VDR (vitamin D receptor) complexed to 1alpha,25(OH)(2)D(3) and the 20-epi analogs(PDB entry [[1ie8]])' scene=''>
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The LBD of a nuclear receptor has a common three layer sandwich
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The structure of the LBD is strongly conserved throughout the familly of nuclear receptors.
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It is completely folded and composed of a beta-sheet, and 12 alpha-helices arranged in a three layered sandwich.
</StructureSection>
</StructureSection>

Revision as of 08:14, 6 September 2012

Contents

Nuclear Receptor

Structure

DBD (DNA Binding Domain)

LBD (Ligand Binding Domain)

Structure of the LBD of a VDR (vitamin D receptor) complexed to 1alpha,25(OH)(2)D(3) and the 20-epi analogs(PDB entry 1ie8)

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Schwarz Benjamin

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