This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Sandbox pia
From Proteopedia
(Difference between revisions)
| Line 4: | Line 4: | ||
Anything in this section will appear adjacent to the 3D structure and will be scrollable. | Anything in this section will appear adjacent to the 3D structure and will be scrollable. | ||
The model displays one half of the symmetric 26S proteasome. The complex consists of a core particle, build out of 4 heptameric rings in the order <math> {/alpha} </math> - <math> /beta </math> - <math>/beta</math> - <math>/alpha</math> | The model displays one half of the symmetric 26S proteasome. The complex consists of a core particle, build out of 4 heptameric rings in the order <math> {/alpha} </math> - <math> /beta </math> - <math>/beta</math> - <math>/alpha</math> | ||
| - | The regulatory particle is divided into a base and a lid. The base are 6 AAA-ATPases (Rpt1-6), Rpn1 whereas the lid consists of non-ATPases containing a PCI domain( Rpn9,5 6 73 12), a MPN domain (Rpn8, 11), Ubiquitin receptors (Rpn10 13) | + | The regulatory particle is divided into a base and a lid. The base are 6 AAA-ATPases (Rpt1-6), Rpn1 whereas the lid consists of non-ATPases containing a PCI domain( Rpn9,5 6 73 12), a MPN<scene name='Sandbox_pia/Mpn/1'>MPN</scene> domain (Rpn8, 11), Ubiquitin receptors (Rpn10 13) |
| + | |||
<scene name='Sandbox_pia/26s_color/1'>TextToBeDisplayed</scene> | <scene name='Sandbox_pia/26s_color/1'>TextToBeDisplayed</scene> | ||
| + | |||
| + | |||
As described before: <ref>pmid 22307589</ref> <ref>pmid 20467039 </ref> | As described before: <ref>pmid 22307589</ref> <ref>pmid 20467039 </ref> | ||
Revision as of 08:55, 6 September 2012
Structural model of yeast 26S
| |||||||||||
- ↑ Lasker K, Forster F, Bohn S, Walzthoeni T, Villa E, Unverdorben P, Beck F, Aebersold R, Sali A, Baumeister W. Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1380-7. Epub 2012 Jan 23. PMID:22307589 doi:10.1073/pnas.1120559109
- ↑ Forster F, Lasker K, Nickell S, Sali A, Baumeister W. Toward an integrated structural model of the 26S proteasome. Mol Cell Proteomics. 2010 Aug;9(8):1666-77. Epub 2010 May 13. PMID:20467039 doi:10.1074/mcp.R000002-MCP201
